Researchers identify key enzyme DNA repair pathway bi13280640 Researchers have discovered an enzyme crucial to a type of DNA repair that also causes resistance to a class of cancer drugs most commonly used against ovarian cancer

'Linc-ing' a noncoding RNA to a central cellular pathway bi13280640 ( Beth Israel Deaconess Medical Center ) The recent discovery of more than a thousand genes known as large intergenic noncoding RNAs (or "lincRNAs") opened up a new approach to understanding the function and organization of the genome. That surprising breakthrough now made even more compelling the finding that dozens of these lincRNAs are induced by p53, the most commonly mutated gene ..

Researchers identify key enzyme DNA repair pathway bi13280640 Researchers have discovered an enzyme crucial to a type of DNA repair that also causes resistance to a class of cancer drugs most commonly used against ovarian cancer

'Linc-ing' a noncoding RNA to a central cellular pathway bi13280640 ( Beth Israel Deaconess Medical Center ) The recent discovery of more than a thousand genes known as large intergenic noncoding RNAs (or "lincRNAs") opened up a new approach to understanding the function and organization of the genome. That surprising breakthrough now made even more compelling the finding that dozens of these lincRNAs are induced by p53, the most commonly mutated gene ..

Super-sizing Cancer Drug Minimizes Side Effects bi13280640 Researchers design a new version of cisplatin that spares the kidneys, letting doctors use higher doses.One of the first chemotherapy drugs given to patients diagnosed cancer especially lung, ovarian or breast cancer cisplatin, a platinum-containing compound that gums up tumor cells DNA. Cisplatin does a good job of killing those tumor cells, but can also seriously damage the ..

Research and Markets: The Future of Molecular Diagnostics: Innovative Technol bi13280640 DUBLIN--(BUSINESS WIRE)--Research and Markets (http://www.researchandmarkets.com/research/f6724e/the_future_of_mole) has announced the addition of the "The Future of Molecular Diagnostics: Innovative Technologies Driving Market Opportunities Personalized Medicine" report to offering. Molecular diagnostics, essentially the analysis of DNA and RNA at the ..

Noisy bacteria bi13280640 Cell-by-cell analysis finds big differences among genetically identical cells..

Mechanism uncovered behind Salmonella virulence and drug susceptibility bi13280640 Researchers have discovered a novel mechanism Salmonella that affects virulence and susceptibility to antibiotics by changing production of proteins a previously unheard of manner. This allows Salmonella to selectively change levels of certain proteins to respond to inhospitable conditions

Scientists uncover mechanism behind Salmonella virulence and drug susceptibility bi13280640 Salmonella can change production of proteins a previously unheard of manner to respond to harsh conditions. Evidence exists for a similar mechanism all 5 kingdoms of life

Spiegel Interview With Craig Venter - 'We Have Learned Nothing From The Genome' bi13280640 Background: Ten years ago, Craig Venter had plenty of reason to feel triumphant

Next generation sequencing establishes genetic link between two rare diseases bi13280640 Scientists have successfully used "next generation sequencing" to identify mutations that may cause a rare and mysterious genetic disorder. The research, published by Cell Press on July 29th the American Journal of Human Genetics, demonstrates that sequencing an affected individual's entire "exome"; that is, all of the genes that carry instructions for producing proteins, can reveal critical ..

Scientists pinpoint a cell-of-origin for human prostate cancer bi13280640 UCLA scientists have identified for the first time a cell-of-origin for human prostate cancer, a discovery that could result better predictive and diagnostics tools and the development of new and more effective targeted treatments for the disease

Super-sizing Cancer Drug Minimizes Side Effects bi13280640 Researchers design a new version of cisplatin that spares the kidneys, letting doctors use higher doses.One of the first chemotherapy drugs given to patients diagnosed cancer especially lung, ovarian or breast cancer cisplatin, a platinum-containing compound that gums up tumor cells DNA. Cisplatin does a good job of killing those tumor cells, but can also seriously damage the ..

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